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1

Mechanisms of Disease: the hygiene hypothesis revisited

Guarner, Francisco, Bourdet-Sicard, Raphaëlle, Brandtzaeg, Per, Gill, Harsharnjit S, McGuirk, Peter, van Eden, Willem, Versalovic, James, Weinstock, Joel V, Rook, Graham AW

Journal:

Nature Clinical Practice Gastroenterology & Hepatology

Year:

2006

Language:

english

File:

PDF, 315 KB

english, 2006

2

Cloning of the mycobacterial epitope recognized by T lymphocytes in adjuvant arthritis

Eden, Willem van, Tholet, Jelle E. R., Zee, Ruurd van der, Noordzij, Alie, van Embden, Jan D. A., Hensen, Evert J., Cohen, Irun R.

Journal:

Year:

1988

File:

PDF, 362 KB

1988

3

Anergic T cells actively suppress T cell responses via the antigen-presenting cell

Leonie S. Taams, Annemiek J. M. L. van Rensen, Martien C. M. Poelen, Cécile A. C. M. van Els, Arit C. Besseling, Josée P. A. Wagenaar, Willem van Eden, Marca H. M. Wauben

Journal:

European Journal of Immunology

Year:

1998

Language:

english

File:

PDF, 223 KB

english, 1998

4

Antigen presentation by T cells versus professional antigen-presenting cells (APC): differential consequences for T cell activation and subsequent T cell-APC interactions

Leonie S. Taams, Willem van Eden, Marca H. M. Wauben

Journal:

European Journal of Immunology

Year:

1999

Language:

english

File:

PDF, 123 KB

english, 1999

5

Induction of experimental autoimmune arthritis by a public epitope of the T cell receptor variable α domain of an arthritogenic T cell clone

Esther A. E. van Tienhoven, Peter J. S. van Kooten, Jetty G. Veenstra, Marein H. van der Hage, Willem van Eden, Chris P. M. Broeren

Journal:

European Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 174 KB

english, 2000

6

Treatment of adjuvant-induced arthritis by oral administration of mycobacterial Hsp65 during disease

Pieter M. Cobelens, Cobi J. Heijnen, Edward E. S. Nieuwenhuis, Peter P. G. Kramer, Ruurd Van Der Zee, Willem Van Eden, Annemieke Kavelaars

Journal:

Arthritis & Rheumatism

Year:

2000

Language:

english

File:

PDF, 273 KB

english, 2000

7

Inhibition of adjuvant-induced arthritis by interleukin-10-driven regulatory cells induced via nasal administration of a peptide analog of an arthritis-related heat-shock protein 60 T cell epitope

Berent J. Prakken, Sarah Roord, Peter J. S. Van Kooten, Josée P. A. Wagenaar, Willem Van Eden, Salvatore Albani, Marca H. M. Wauben

Journal:

Arthritis & Rheumatism

Year:

2002

Language:

english

File:

PDF, 208 KB

english, 2002

8

Immune regulation in adjuvant-induced arthritis: Possible implications for innovative therapeutic strategies in arthritis

Willem van Eden, Byron H. Waksman

Journal:

Arthritis & Rheumatism

Year:

2003

Language:

english

File:

PDF, 85 KB

english, 2003

9

T lymphocyte clones illuminate pathogenesis and affect therapy of experimental arthritis

Irun R. Cohen, Joseph Holoshitz, Willem van Eden, Ayalla Frenkel

Journal:

Arthritis & Rheumatism

Year:

1985

Language:

english

File:

PDF, 602 KB

english, 1985

10

Histopathology of arthritis induced in rats by active immunization to mycobacterial antigens or by systemic transfer of t lymphocyte lines. a light and electron microscopic study of the articular surface using cationized ferritin

Ritta Stanescu, Ofer Lider, Willem Van Eden, Joseph Holoshitz, Irun R. Cohen

Journal:

Arthritis & Rheumatism

Year:

1987

Language:

english

File:

PDF, 1.97 MB

english, 1987

11

Increased arthritis susceptibility in cartilage proteoglycan–specific T cell receptor–transgenic mice

Suzanne E. Berlo, Teun Guichelaar, Corlinda B. ten Brink, Peter J. van Kooten, Femke Hauet-Broeren, Katalin Ludanyi, Willem van Eden, Chris P. Broeren, Tibor T. Glant

Journal:

Arthritis & Rheumatism

Year:

2006

Language:

english

File:

PDF, 348 KB

english, 2006

12

A novel heat-shock protein coinducer boosts stress protein Hsp70 to activate T cell regulation of inflammation in autoimmune arthritis

Lotte Wieten, Ruurd van der Zee, Rachel Spiering, Josée Wagenaar-Hilbers, Peter van Kooten, Femke Broere, Willem van Eden

Journal:

Arthritis & Rheumatism

Year:

2010

Language:

english

File:

PDF, 173 KB

english, 2010

13

Complement regulatory protein Crry/p65 costimulation expands natural Treg cells with enhanced suppressive properties in proteoglycan-induced arthritis

Gloria Ojeda, Eliana Pini, César Eguiluz, María Montes-Casado, Femke Broere, Willem van Eden, Jose M. Rojo, Pilar Portolés

Journal:

Arthritis & Rheumatism

Year:

2011

Language:

english

File:

PDF, 746 KB

english, 2011

14

Efficient mapping and characterization of a T cell epitope by the simultaneous synthesis of multiple peptides

Ruurd Van Der Zee, Willem Van Eden, Rob H. Meloen, Alie Noordzij, Jan D. A. Van Embden

Journal:

European Journal of Immunology

Year:

1989

Language:

english

File:

PDF, 547 KB

english, 1989

15

Efficient recognition by rat T cell clones of an epitope of mycobacterial hsp 65 inserted in Escherichia coli outer membrane protein PhoE

Els J. M. Hogervorst, Marja Agterberg, Josée P. A. Wagenaar, HenriëTte Adriaanse, Claire J. P. Boog, Ruurd Van Der Zee, Jan D. A. Van Embden, Willem Van Eden, Jan Tommassen

Journal:

European Journal of Immunology

Year:

1990

Language:

english

File:

PDF, 638 KB

english, 1990

16

Conserved nucleotide sequences at the 5' end of T cell receptor variable genes facilitate polymerase chain reaction amplification

Chris P. M. Broeren, Willem van Eden, Johannes G. Kusters, Johannes A. Lenstra, Georges M. G. M. Verjans, Ton Logtenberg

Journal:

European Journal of Immunology

Year:

1991

Language:

english

File:

PDF, 632 KB

english, 1991

17

T cell reactivity to an epitope of the mycobacterial 65-kDa heat-shock protein (hsp 65) corresponds with arthritis susceptibility in rats and is regulated by hsp 65-specific cellular responses

Els J. M. Hogervorst, Claire J. P. Boog, Josée P. A. Wagenaar, Marca H. M. Wauben, Ruurd van der Zee, Willem van Eden

Journal:

European Journal of Immunology

Year:

1991

Language:

english

File:

PDF, 827 KB

english, 1991

18

Synovial fluid-derived Yersinia-reactive T cells responding to human 65-kDa heat-shock protein and heat-stressed antigen-presenting cells

Elisabeth Hermann, Ansgar W. Lohse, Ruurd Van Der Zee, Willem Van Eden, Werner J. Mayet, Peter Probst, Thomas Poralla, Karl-Hermann Meyer zum Büschenfelde, Bernhard Fleischer

Journal:

European Journal of Immunology

Year:

1991

Language:

english

File:

PDF, 546 KB

english, 1991

19

Inhibition of entire myelin basic protein-induced experimental autoimmune encephalomyelitis in Lewis rats by major histocompatibility complex class II-binding competitor peptides

Marca H. M. Wauben, Alexander Kozhich, Irma Joosten, Angelique Schlief, Claire J. P. Boog, Willem Van Eden

Journal:

European Journal of Immunology

Year:

1994

Language:

english

File:

PDF, 880 KB

english, 1994

20

Inhibition of experimental autoimmune myasthenia gravis by major histocompatibility complex class II competitor peptides results not only in a suppressed but also in an altered immune response

Marca H. M. Wauben, Astrid C. W. E. Hoedemaekers, Yvo M. F. Graus, Josee P. A. Wagenaar, Willem van Eden, Marc H. De Baets

Journal:

European Journal of Immunology

Year:

1996

Language:

english

File:

PDF, 1.07 MB

english, 1996

21

Identification of a CD4+CD25+ T cell subset committed in vivo to suppress antigen-specific T cell responses without additional stimulation

Esther N. M. Nolte-‘t Hoen, Josée P. A. Wagenaar-Hilbers, Elmieke P. J. Boot, Chia-Huey Lin, Ger J. A. Arkesteijn, Willem van Eden, Leonie S. Taams, Marca H. M. Wauben

Journal:

European Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 347 KB

english, 2004

22

Uptake of membrane molecules from T cells endows antigen-presenting cells with novel functional properties

Esther N. M. Nolte-‘t Hoen, Josée P. A. Wagenaar-Hilbers, Peter J. Peters, Bart M. Gadella, Willem van Eden, Marca H. M. Wauben

Journal:

European Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 373 KB

english, 2004

23

Effector and regulatory T cells derived from the same T cell clone differ in MHC class II-peptide multimer binding

Esther N. M. Nolte-‘t Hoen, Maria Grazia Amoroso, Jetty Veenstra, Mayken C. Grosfeld-Stulemeyer, Willem van Eden, Chris P. M. Broeren, Marca H. M. Wauben

Journal:

European Journal of Immunology

Year:

2004

Language:

english

File:

PDF, 309 KB

english, 2004

24

Translating immunological tolerance into therapy

Berent J. Prakken, Salvatore Albani, Willem van Eden

Journal:

European Journal of Immunology

Year:

2007

Language:

english

File:

PDF, 76 KB

english, 2007

25

Low cross-reactivity of T-cell responses against lipids from Mycobacterium bovis and M. avium paratuberculosis during natural infection

Ildiko Van Rhijn, Thi Kim Anh Nguyen, Anita Michel, Dave Cooper, Marc Govaerts, Tan-Yun Cheng, Willem van Eden, D. Branch Moody, Jacobus A. W. Coetzer, Victor Rutten, Ad P. Koets

Journal:

European Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 308 KB

english, 2009

26

Heat shock proteins: Immunity and immunopathology

Peter M. Lydyard, Willem van Eden

Journal:

Immunology Today

Year:

1990

Language:

english

File:

PDF, 823 KB

english, 1990

27

The production of monoclonal antibodies to rat T cell receptors

Jetty G. Veenstra, Peter J.S. van Kooten, Willem van Eden, Chris P.M. Broeren

Journal:

Immunology Letters

Year:

1997

Language:

english

File:

PDF, 176 KB

english, 1997

28

Do heat shock proteins control the balance of T-cell regulation in inlammatory diseases?

Willem van Eden, Ruurd van der Zee, Alberta G.A Paul, Berent J Prakken, Uwe Wendling, Stephen M Anderton, Marca H.M Wauben

Journal:

Immunology Today

Year:

1998

Language:

english

File:

PDF, 157 KB

english, 1998

29

Preface

Willem van Eden

Journal:

Year:

1998

Language:

english

File:

PDF, 61 KB

english, 1998

30

Nasal administration of arthritis-related T cell epitopes of heat shock protein 60 as a promising way for immunotherapy in chronic arthritis

Berent Prakken, Marca Wauben, Peter van Kooten, Steve Anderton, Ruurd van der Zee, Wietse Kuis, Willem van Eden

Journal:

Year:

1998

Language:

english

File:

PDF, 610 KB

english, 1998

31

Heat shock protein 60 and adjuvant arthritis: a model for T cell regulation in human arthritis

Berent J. Prakken, Sarah Roord, Arash Ronaghy, Marca Wauben, Salvatore Albani, Willem van Eden

Journal:

Seminars in Immunopathology

Year:

2003

Language:

english

File:

PDF, 195 KB

english, 2003

32

Heat shock proteins in juvenile idiopathic arthritis: Keys for understanding remitting arthritis and candidate antigens for immune therapy

Berent Prakken, Wietse Kuis, Willem van Eden, Salvatore Albani

Journal:

Current Rheumatology Reports

Year:

2002

Language:

english

File:

PDF, 1.25 MB

english, 2002

33

Hsp70 expression and induction as a readout for detection of immune modulatory components in food

Lotte Wieten, Ruurd van der Zee, Renske Goedemans, Jeroen Sijtsma, Mauro Serafini, Nicolette H. Lubsen, Willem van Eden, Femke Broere

Journal:

Cell Stress and Chaperones

Year:

2010

Language:

english

File:

PDF, 508 KB

english, 2010

34

Caught with their PAMPs down? The extracellular signalling actions of molecular chaperones are not due to microbial contaminants

Brian Henderson, Stuart K. Calderwood, Anthony R. M. Coates, Irun Cohen, Willem van Eden, Thomas Lehner, A. Graham Pockley

Journal:

Cell Stress and Chaperones

Year:

2010

Language:

english

File:

PDF, 566 KB

english, 2010

35

Peptide induced nasal tolerance for a mycobacterial hsp60 T cell epitope in rats suppresses both adjuvant arthritis and non-microbially induced experimental arthritis

Peter J.S. van Kooten, Berent J. Prakken, Ruurd van der Zee, Stephen M. Anderton, Wietse Kuis, Willem van Eden

Journal:

Immunology Letters

Year:

1997

Language:

english

File:

PDF, 173 KB

english, 1997

36

Intervention in autoimmunity with a DNA vaccine encoding the T cell receptor β chain

Esther A.E. van Tienhoven, Jetty G. Veenstra, Willem van Eden, Chris P.M. Broeren

Journal:

Immunology Letters

Year:

1997

Language:

english

File:

PDF, 177 KB

english, 1997

37

Presentation of the candidate rheumatoid arthritis autoantigen aggrecan by antigen-specific B cells induces enhanced CD4+ T helper type 1 subset differentiation

Caroline L. Wilson, Dominic W. Hine, Ariel Pradipta, Jeffrey P. Pearson, Willem van Eden, John H. Robinson, Andrew M. Knight

Journal:

Year:

2012

Language:

english

File:

PDF, 455 KB

english, 2012

38

(Altered) Self Peptides and the Regulation of Self Reactivity in the Peripheral T cell Pool

Willem van Eden, Stephen M. Anderton, Ruurd van der Zee, Berent J. Prakken, Chris P. M. Broeren, Marca H. M. Wauben

Journal:

Immunological Reviews

Year:

1996

Language:

english

File:

PDF, 4.45 MB

english, 1996

39

Heat-shock protein T-cell epitopes trigger a spreading regulatory control in a diversified arthritogenic T-cell response

Willem van Eden, Ruurd van der Zee, Leonie S. Taams, A. Berent J. Prakken, Joël van Roon, Marca H. M. Wauben

Journal:

Immunological Reviews

Year:

1998

Language:

english

File:

PDF, 3.27 MB

english, 1998

40

Coimmunization of MHC Class II Competitor Peptides during Experimental Autoimmune Myasthenia Gravis Induction Resulted Not Only in a Suppressed, but Also in an Altered Immune Response

MARCA H. M. WAUBEN, ASTRID C. W. E. HOEDEMAEKERS, YVO M. F. GRAUS, JOSEE P. A. WAGENAAR, WILLEM VAN EDEN, MARC H. DE BAETS

Journal:

Annals of the New York Academy of Sciences

Year:

1998

Language:

english

File:

PDF, 360 KB

english, 1998

41

Interleukin-4 therapy of psoriasis induces Th2 responses and improves human autoimmune disease

Ghoreschi, Kamran, Thomas, Peter, Breit, Susanne, Dugas, Martin, Mailhammer, Reinhard, van Eden, Willem, van der Zee, Ruurd, Biedermann, Tilo, Prinz, Jörg, Mack, Matthias

Journal:

Nature Medicine

Year:

2002

Language:

english

File:

PDF, 619 KB

english, 2002

42

Heat-shock proteins induce T-cell regulation of chronic inflammation

van Eden, Willem, van der Zee, Ruurd, Prakken, Berent

Journal:

Nature Reviews Immunology

Year:

2005

Language:

english

File:

PDF, 380 KB

english, 2005

43

Heat shock proteins are no DAMPs, rather 'DAMPERs'

Broere, Femke, van der Zee, Ruurd, van Eden, Willem

Journal:

Nature Reviews Immunology

Year:

2011

Language:

english

File:

PDF, 96 KB

english, 2011

44

Heat-Shock Proteins as Immunogenic Bacterial Antigens with the Potential to Induce and Regulate Autoimmune Arthritis

Willem Van Eden

Journal:

Immunological Reviews

Year:

1991

Language:

english

File:

PDF, 7.90 MB

english, 1991

45

Stress, Heat Shock Proteins, and Autoimmunity : How Immune Responses to Heat Shock Proteins Are to Be Used for the Control of Chronic Inflammatory Diseases

WILLEM VAN EDEN, GEORGE WICK, SALVATORE ALBANI, IRUN COHEN

Journal:

Annals of the New York Academy of Sciences

Year:

2007

Language:

english

File:

PDF, 122 KB

english, 2007

46

Induction of T Cell Anergy by Liposomes with Incorporated Major Histocompatibility Complex (MHC) II/Peptide Complexes

Annemiek J. M. L. van Rensen, Leonie S. Taams, Mayken C. Grosfeld-Stulemeyer, Willem van Eden, Daan J. A. Crommelin, Marca H. M. Wauben

Journal:

Pharmaceutical Research

Year:

2000

Language:

english

File:

PDF, 326 KB

english, 2000

47

Liposomes with Incorporated MHC Class Il/Peptide Complexes as Antigen Presenting Vesicles for Specific T Cell Activation

Annemiek J. M. L. van Rensen, Marca H. M. Wauben, Mayken C. Grosfeld-Stulemeyer, Willem van Eden, Daan J. A. Crommelin

Journal:

Pharmaceutical Research

Year:

1999

File:

PDF, 1.42 MB

1999

48

A case of mistaken identity: HSPs are no DAMPs but DAMPERs

Willem van Eden, Rachel Spiering, Femke Broere, Ruurd van der Zee

Journal:

Cell Stress and Chaperones

Year:

2012

Language:

english

File:

PDF, 351 KB

english, 2012

49

An enzyme-linked immunosorbent assay for the determination of chloramphenicol using a monoclonal antibody Application to residues in swine muscle tissue

Cornelis van de Water, Nel Haagsma, Peter J. S. van Kooten, Willem van Eden

Journal:

European Food Research and Technology

Year:

1987

Language:

english

File:

PDF, 557 KB

english, 1987

50

T cell regulation in autoimmune arthritis: Possibilities for immunological intervention

Willem van Eden

Journal:

Immunologic Research

Year:

1990

Language:

english

File:

PDF, 513 KB

english, 1990